U.S. Develops Smart Transgenic Rats

American scientists have developed transgenic mice that produce more proteins in their brains that stimulate the growth of nerve fibers and have a stronger ability to learn. In the labyrinth experiments, the transgenic rats had much higher foraging ability than the ordinary rats, and at the same time, the memories of the food storage place in the maze were more clearly remembered. Through the development of transgenic mice, scientists further realized the importance of nerve growth in promoting brain function.
Transgenic mice breeders are professors and professors at Northwestern University, Professor Ariel Thunberg, who transplanted a newly discovered gene to mice. The gene promotes the overproduction of growth-related proteins called GAP-43 in the brain of transgenic mice. The protein acts on nerve endings, stimulates nerve growth, and provides more resources for brain memory functions.
In a labyrinth test of ability to memorize food sites, transgenic mice that overproduced CAP-43 protein in the brain performed better than normal rats with normal protein levels. In addition, the difference between the ability of transgenic mice and common mice appears to be greater at each test interval.
Scientists believe that the above study of transgenic mice has some clues about how memory works, and it may eventually be used to treat diseases related to brain degeneration and disorders, such as Alzheimer's disease.
The gene transplanted into experimental mice was the second single gene discovered by scientists to be able to effectively improve learning and memory. In September 1999, another U.S. research team confirmed that the gene called NR2B kept rats brains "young."

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