Am J Gastroenterol: A simple blood test can help diagnose pancreatic cancer

Release date: 2014-10-31

Recently, a cancer researcher from Indiana University found that a simple blood test may help diagnose pancreatic cancer. The research results are published in the American Journal of Gastroenterology .

Researcher Professor Myles Brand said that pancreatic cancer is the most lethal cancer. In this paper, we found that some microRNAs have higher circulating levels in the blood of patients with pancreatic cancer, so the level of microRNAs circulating in the blood is determined. It can help determine if a patient has pancreatic cancer.

Increased expression of miRNA-10b, miRNA-155, and miRNA-106b can be accurately detected in the body of pancreatic ductal adenocarcinoma, which is by far the most malignant pancreatic cancer. In the article, the researchers collected 215 patients' plasma, bile, and pancreatic fluid for testing, and were supplemented with endoscopy to help diagnose. Korc said that in the future we may be able to determine the risk of pancreatic cancer in individuals by conducting simple blood tests. It is also important to find special markers for early diagnosis of pancreatic cancer. Based on the above findings, this new detection technique may be Used to distinguish between pancreatic cancer and other pancreatitis.

The discovery of new markers is also a major advancement in scientists' efforts to combat metastatic pancreatic cancer, as current therapies only extend the lifespan of patients by 6 to 16 weeks; pancreatic cancer is difficult to detect and diagnose because it has no symptoms at an early stage And the position of the pancreas is relatively concealed, so it is generally difficult to detect the lesions of the pancreas. Only 6% of patients with pancreatic cancer have a survival period of more than 5 years, and data from the National Cancer Center show that there were approximately 46,420 new cases in 2014, of which 39,590 individuals died of the disease.

Source: Bio Valley

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