Use time and dose of probiotics

With the gradual acceptance of microecological agents, their use has become more and more extensive. The following describes the use time and dose of microecological agents as follows.

First, the use of time

Microecological preparations can be used throughout the animal's growth process, but their effects are not the same at different growth stages. Generally in animal larvae, the microecological balance in vivo is not yet fully established, and the ability to resist diseases is weak. At this time, probiotics can be introduced into the body and occupy the attachment points with the best effect. For example, the increase in the number of beneficial microbial populations in the intestinal tract of newborn ruminants not only promotes the digestion of cellulose by host animals, but also helps to prevent pathogenic microorganisms from attacking the intestines. Like other newly born mammals, the gastrointestinal tract of newborn ruminants is not yet fully developed, but the colonization of bacteria in the intestine is quite rapid. Lactobacilli and streptococci are present at 24 hours of birth, and at the age of 1 week, the total number of lactobacilli in the intestine is measured. 107~109/g. In addition, microecological balance in animals is destroyed under conditions of weaning, transportation, feed conversion, weather mutation, and poor feeding environment. The use of microecological agents is extremely beneficial to the formation of dominant populations. To grasp the timing of the application of probiotics, as soon as possible and long-term feeding, to fully reflect its probiotic effect.

Second, the use of dose

The probiotic effect of the microecological preparation is achieved through a series of physiological activities of beneficial microorganisms in the animal body. The final effect is closely related to the number of probiotics applied, and the number is not enough. The advantage of the flora cannot be formed in the body and it is difficult to play a probiotic role. . According to experiments, if the concentration of a bacterium in the cecum content of a bacterium is below 107/g, the enzyme and metabolite produced by the bacterium will not be sufficient to affect the host; if the amount is too large, it will exceed the need to occupy the intestine attachment point and form the dominant flora. The amount of bacteria will not only increase the effectiveness, but will cause unnecessary waste. There is no uniform requirement for the number of microflora used for specific cultured animals. German scholars believe that the amount of bacteria contained in the feed for piglets should reach (0.2~0.5)107/g feed. Adding 106 Bacillus per gram to the finishing pig feed, the E. coli in the feces decreased by 35%, 0.5 to 0.6g per day can have a therapeutic effect, while Lactobacillus differs depending on the preparation, and its number is not less than 107 /g, apply 0.1 ~ 3g daily, the general amount of 0.02% ~ 0.2%.

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