H7N9 detection reagents have been produced in volume

On the 3rd, Jiangsu Province reported that 4 cases of human infection with H7N9 bird flu were found. In Shanghai and Anhui provinces, 3 cases of H7N9 bird flu were previously reported.

On the same day, the Shanghai Municipal Government held a press conference to introduce the progress of the prevention and control of the epidemic. It answered questions from the outside world about “the discovery of the case and confirmed the release of more than 20 days.” At the same time, Shanghai has not yet received a new report of unexplained pneumonia. It has also changed from "weekly report" to "daily report".

Wu Fan, director of the Shanghai Center for Disease Control and Prevention, said in response to a reporter's question that there were no relevant links between the three cases that had been discovered.

An epidemiologist said that China's disease control system, especially the national influenza surveillance reporting network and laboratory capabilities, have been improving in the past 10 years and have the ability to quickly respond to and prevent new viruses. He said that a test kit for H7N9 has been developed and started mass production.

While strengthening prevention and control of the epidemic in various areas, the clinical response to H7N9 and the development of vaccines are also the focus of public attention.

Sources To be determined influenza virus can be divided into A (A), B (B), C (C) three types. Among them, Influenza A can be divided into HxN x 135 subtypes based on influenza virus characteristics. H7N9 subtype avian influenza virus is one of them. It was found only in poultry and no infection was found.

According to the official report, a total of 7 cases have been found. According to the notification of the National Sanitation and Family Planning Commission on March 31, three cases of H7N9 bird flu were found in Shanghai and Anhui provinces, of which two cases died after being rescued and the other patient was actively treated in Nanjing. Yesterday, Jiangsu Province reported 4 cases.

The Disease Control Office of the Beijing Municipal Health Bureau said yesterday that no such cases have been found in Beijing and no patients with unexplained pneumonia have been found. The local H7N9 virus has been included in the infectious disease surveillance network.

A virus expert said that the human infected H7N9 virus is a new reassortant virus. The two gene segments of the virus are from the H7N9 virus among poultry, and there are six internal H9N2 viruses from the poultry. There is no pig. The gene fragment.

The China Center for Disease Control and Prevention also said that the H7N9 subtype influenza virus was previously found only in poultry, and there have been outbreaks among poultry in the Netherlands, Japan and the United States, but no human infections have been found.

The above-mentioned epidemiologist said that the kit for H7N9 has been developed, and it has begun mass production and was sent to various places as soon as possible. In addition to screening for H3N2, H1N1 seasonal influenza virus, H5N1 bird flu virus, etc., it will also be screened. Check the new virus H7N9.

The staff of the Beijing CDC said that it has received a test kit.

There is currently no vaccine against the H7N9 bird flu virus.

The source problem of H7N9 is another difficult problem to tackle.

Whether or not the source of speculation from the outside world is from dead pigs in Shanghai's Huangpu River, the Deputy Director of the Shanghai Municipal Agriculture Commission Yin Ou emphasized at the press conference that the Municipal Commission of Agriculture had organized the relevant departments on April 1st, for the 34 previous salvage floats. The dead pig samples were tested according to relevant national regulations. The results showed that no bird flu virus was found.

Wu Fan said that it is still not clear and clear enough to tell whether it was humans infected with the virus of poultry, or whether the virus of poultry has turned into a human flu virus through mutation and genetic recombination.

Influenza virus is divided into human influenza virus, bird flu virus, and swine flu virus. "Between poultry and livestock, we haven't seen any cases of H7N9 spreading from our perspective," Wu Fan said.

"If only a very small number of birds carry the virus, it will not cause the outbreak to occur. However, it is very difficult to detect the disease," said an expert on agricultural diseases. For some animal epidemics, it was initially difficult to find. However, the expert emphasized that the current prevention and control and quarantine chain is still relatively complete. County and townships now have veterinary stations. If an outbreak occurs, they will report to the province, go to the province for sampling, and then go to the province for testing. Finally, after the country Level reference laboratory to confirm.

Strengthen the epidemic prevention For more than 20 days before the announcement of H7N9 infection, Wu Fan clarified that it takes time for confirmed cases to reach the diagnosis.

H7N9 is a new type of virus that is infected in humans. The discovery process includes general clinical diagnosis, elimination of known pathogens, detection of new pathogens of unknown cause, and sequencing of virus-related sequence genes. At the end, it should be clear that at least 20 Many days.

In addition, Wu Fan said that the detection of unknown pathogens is quite difficult, according to the method of gene sequencing. The sequencing of the gene was also compared with related gene sequences that are currently known internationally. It was found that the virus had not previously appeared in humans.

Yin Ou said that the Shanghai Animal Disease Control Center has been organized to conduct a thorough investigation of poultry in the city. So far, no bird flu outbreak has been found in poultry.

The conference also reported that, since yesterday, Shanghai has launched a three-level response to the influenza epidemic contingency plan. The relevant departments of the city and the city's medical and health institutions have invested in monitoring and preventing and controlling the flu epidemic.

The emergency contingency plan for influenza is divided into four levels, with the fourth being the lightest and the highest being the first.

Xu Jianguang, director of the Shanghai Municipal Health Planning Commission, said that after Shanghai launched the three-level influenza emergency plan, Shanghai Municipal Public Health Clinical Center was designated as a municipal-level designated medical institution. Various types of medical institutions at all levels will strengthen the establishment of outpatient clinics and, after discovering cases that meet the definition of unexplained pneumonia, will promptly initiate reports and disposal procedures.

In addition, 43 influenza surveillance sites in the city and 130 medical institutions that have established fever clinics have changed the frequency of unsolicited pneumonia active search from the implementation of the “weekly report” system to the “daily report” system.

The ward heard that the Department of Health of Jiangsu Province reported on the 2nd that 4 cases of H7N9 cases were diagnosed in this province. At present, the patient is in critical condition and is fully trying to rescue him.

The 4 patients were respectively from Jiangning District, Nanjing, Suyang County, Suqian City, Wujiang District, Suzhou City, and Changzhou (now living in Binhu District, Wuxi). Among them, the first two were admitted to a hospital in Nanjing. In addition, Han, who had been transferred from Anhui to Nanjing for treatment, had 3 cases of H7N9 virus patients currently undergoing emergency treatment at a local hospital in Nanjing.

According to the information released by the Jiangsu Provincial Department of Health, Xu, a female patient from Jiangning District of Nanjing, is 45 years old and is engaged in slaughter of live poultry. On March 19th, symptoms such as fever, dizziness, and body aches and fatigue were reported. On the morning of March 27th, due to aggravation of the condition, ICU treatment was transferred to a hospital in Nanjing. Another female patient from Sangyang County in Suqian City, Sang Mou, is 48 years old and works in sheet metal processing. On March 19, fever, dizziness, and cough were observed. On March 30th, the patient transferred to the ICU of a hospital in Nanjing for treatment.

In the ICU intensive care unit on the fifth floor of the new building of the Nanjing Drum Tower Hospital, the gate of the ICU was closed, but various staff members often entered. In less than an hour, there were only a few medical staff who had sent in and out of the report and cleaning staff who took the equipment.

However, it has not been confirmed from the hospital to the hospital to treat patients with H7N9. A doctor told directly: "The health department has verbally ordered the hospital to not disclose any information to the public."

On the evening of the same day, two doctors dressed in white coats accompanied the two security guards to go to the ICU ward door, and then walked into the ICU ward. The security guard who stayed outside told the reporter that one of the doctors was the director of Drum Tower Hospital. Another security guard said that the Dean would not personally enter the ICU ward rounds.

The University of Southeast University Affiliated Zhongda Hospital is not far from Drum Tower Hospital. When I arrived at the hospital's ICU ward, which was the fifth floor of the new building, the ICU outside the visiting time was empty. A doctor said: "Any information about bird flu must be approved by the hospital's medical department or propaganda department before it can be disclosed."

A list of "Total Inpatient Expenses and Balances" posted on the door was found outside the ICU. The update date was 14:21 on April 2. Among the 35 ICU patients, there is a female surnamed Han. The type of patient is ordinary, non-commercial medical insurance or municipal dry insurance.