Graphical grading problem in pharmaceutical smash
The pulverized material is difficult to achieve the required particle size requirement by mechanical pulverization at one time, and is often in a large particle size distribution range. In the process, only a part of the products meet the particle size requirements, while the other products do not meet the particle size requirements. If these products have not been separated in time, and they are crushed together with the products that do not meet the requirements, It will cause energy waste and excessive crushing of some products [1]. To this end, a comminution grading technique is produced.
The ordinary powder can be classified by sieving method. At present, the pore size of the zui fine screen is only about 20 μm (600 mesh). Considering the clogging problem of the screening process, the actual screening of more than 325 mesh has no industrial significance [1]. In order to meet people's requirements for crushing particle size, especially the pharmaceutical industry has further requirements for powder particle size. As a result, more grading techniques have entered the crushing city.
According to the type of equipment used, it can be divided into: dry mechanical classification (such as impeller type, turbine type), cyclone type classification, dish type classification, horizontal spiral classification, electrostatic field classification, supercritical classification, and the like. The following is a summary of the two commonly used zui.
1, a dry mechanical classifying <br> <br> grading machine are generally dry to dry air as a medium. The starting point is to improve the classification efficiency and reduce the classification particle size by various mechanical means. Usually, various mechanical motion devices are introduced into the classification equipment at various levels to increase the centrifugal force of the particles in the classifier, to improve the separation factor, increase the classification speed, and improve the classification accuracy [1].
1.1, disc type classifier
The principle (as shown in Figure 1): During the work, the graded powder enters the center surface of the high-speed rotating disc. Under the action of centrifugal force, the coarse particles are thrown to the periphery of the disc, and the fine particles are at the center of the disc, then The coarse and fine particles are respectively discharged through different channels.
The exit is discharged. The fine particles are discharged from the impeller slit through the fine particle outlet due to the centripetal force greater than the centrifugal force, and are collected by the post-process collector.
The MS impeller classifier was developed by Japan's Hosokawa Co., Ltd., and the company further improved the MS-H type, MS-N type, MSS type and other classifiers.
1.3. ATP type classifier The ATP type classifier is an impeller rotor type classifier. The principle (as shown in Fig. 2): the pulverized indoor powder is fed into the impeller rotor in a fluidized state under the action of negative pressure airflow. area. Under the centrifugal force generated by the high-speed rotation of the impeller, the suction generated by the negative pressure airflow, the gravity of the particles and the lift generated by the rising airflow, the coarse-grained material falls into the pulverizing chamber and is pulverized again, and then re-graded with the airflow. The fine particles are sucked away by the airflow from the gap between the impellers, and then collected by components such as a cyclone.
2, cyclone classification <br> <br> cyclone classification technology applies to both dry classification but also for wet classification and dry classification here mainly to talk about.
Granulator 4
The ordinary powder can be classified by sieving method. At present, the pore size of the zui fine screen is only about 20 μm (600 mesh). Considering the clogging problem of the screening process, the actual screening of more than 325 mesh has no industrial significance [1]. In order to meet people's requirements for crushing particle size, especially the pharmaceutical industry has further requirements for powder particle size. As a result, more grading techniques have entered the crushing city.
According to the type of equipment used, it can be divided into: dry mechanical classification (such as impeller type, turbine type), cyclone type classification, dish type classification, horizontal spiral classification, electrostatic field classification, supercritical classification, and the like. The following is a summary of the two commonly used zui.
1, a dry mechanical classifying <br> <br> grading machine are generally dry to dry air as a medium. The starting point is to improve the classification efficiency and reduce the classification particle size by various mechanical means. Usually, various mechanical motion devices are introduced into the classification equipment at various levels to increase the centrifugal force of the particles in the classifier, to improve the separation factor, increase the classification speed, and improve the classification accuracy [1].
1.1, disc type classifier
Granulator 1
The principle (as shown in Figure 1): During the work, the graded powder enters the center surface of the high-speed rotating disc. Under the action of centrifugal force, the coarse particles are thrown to the periphery of the disc, and the fine particles are at the center of the disc, then The coarse and fine particles are respectively discharged through different channels.
The exit is discharged. The fine particles are discharged from the impeller slit through the fine particle outlet due to the centripetal force greater than the centrifugal force, and are collected by the post-process collector.
The MS impeller classifier was developed by Japan's Hosokawa Co., Ltd., and the company further improved the MS-H type, MS-N type, MSS type and other classifiers.
1.3. ATP type classifier The ATP type classifier is an impeller rotor type classifier. The principle (as shown in Fig. 2): the pulverized indoor powder is fed into the impeller rotor in a fluidized state under the action of negative pressure airflow. area. Under the centrifugal force generated by the high-speed rotation of the impeller, the suction generated by the negative pressure airflow, the gravity of the particles and the lift generated by the rising airflow, the coarse-grained material falls into the pulverizing chamber and is pulverized again, and then re-graded with the airflow. The fine particles are sucked away by the airflow from the gap between the impellers, and then collected by components such as a cyclone.
Granulator 2
2, cyclone classification <br> <br> cyclone classification technology applies to both dry classification but also for wet classification and dry classification here mainly to talk about.
Granulator 3
Dry cyclone grading (as shown in Figure 3) is based on the use of gas as a medium and as a power source, using a combination of centrifugal force field and gravity field. In the grading process, the high-speed air stream carries the graded powder from The separator enters the separator tangentially, and the airflow rotates along the inner wall of the circular separator at a high speed. Under the action of strong centrifugal force, the coarse particles in the powder are rotated downward along the inner wall of the cone of the separator and are discharged to the lower discharge port; The fine particles are concentrated toward the center of the separator due to the action of the centripetal force and rise with the gas flow, and are discharged from the upper outlet, thereby achieving the purpose of classifying the coarse and fine particles.
Granulator 4
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