Science and Technology Daily, Washington, March 26 (Reporter Liu Haiying) The collaboration between the University of California at Berkeley and the Clare Institute of Claremont combines gene editing technology with nanoelectronics to create a test that can be detected in minutes. A new type of handheld device with specific genetic mutations. Researchers say the device called "CRISPR-Chip" is fast and easy to use to quickly diagnose genetic diseases or to assess the accuracy of gene editing techniques. The CRISPR-Cas9 technology that has emerged in recent years is known for its precision and provides researchers with unprecedented gene editing capabilities. To take advantage of CRISPR's gene targeting capabilities, the team connected an inactivated Cas9 protein variant, a Cas9 variant that finds a specific site in DNA but does not cut it, to a graphene-made On the transistor. When such a CRISPR complex finds a specific site in its targeted DNA, it binds to it and triggers a change in graphene conductivity, changing the electrical properties of the transistor. These changes can be detected by hand-developed handheld devices. Researchers point out that it is not difficult to detect a genetic mutation by DNA sequencing today, and many hospitals or companies can provide such services. However, genetic mutation detection with “CRISPR-Chip†is easier and faster than most genetic tests, and can be performed in a doctor's office or in a field work environment without sending samples to the laboratory. When you use it, you only need to put the extracted DNA sample on the chip. Search by CRISPR technology, the graphene transistor can report the search results in a few minutes. The researchers say that the new device is a combination of nanoelectronics and modern biology, combining the precision of CRISPR technology with the ultra-sensitivity of graphene transistors, which is both accurate and fast. The device can be used to quickly diagnose diseases, to help doctors develop personalized treatment plans for patients with rapid genetic testing, and to monitor whether CRISPRs bind to specific DNA sequences, thereby assessing the accuracy of CRISPR-based gene editing techniques. Related research results were published online in the recent issue of Nature·Biomedical Engineering. Editor-in-chief Compared with rapid diagnosis and genetic testing, the authors value the accuracy of CRISPR-based gene editing technology. At present, the reason why this technology is used by the application is limited by the application, because it has a certain proportion of off-target problems in practical applications. Therefore, spare no effort to improve the accuracy of editing is exactly what makes CRISPR “Genetic Devil†the ultimate potential of tool-based technology. Source: Technology Daily
The material of this scar sticker consists of a silicone gel, usually skin-colored in appearance, and is indicated for scar recovery treatment and prevention.It is prohibited to be used before the wound has healed. Allergic reaction to silicone rubber material is prohibited. Car scar stickers prevent the scars from proliferation effectively, soften and smooth the scars effectively. Scar car sticker relieve pruritus and pain quickly. Scar removing sticker Moisturizing and breathable, realistick scars sticker is reusable and washable; Comfortable, ultra-thin fabric,Safe and effective; scar patch sticker without latex and drug free; Before use this product, clean the scar area or wipe it with a cotton swab dipped in 75% alcohol to disinfect it before use, and let it dry. Open the package, remove lion king scar stickers and cut the scar patch to the right size. Remove the backing film and stick the sticky side on the scar. Blue scar silicone sticker can be continuously pasted on the scar surface until the stickiness disappears.
Scar Stickers,Fake Wound Stickers,Silicone Gel Dressing,Silicone Gel Scar Dressing Henan Maidingkang Medical Technology Co.,Ltd , https://www.mdkmedical.com
Just put the DNA sample on the chip and check out the new mutation on the chip.
:2019-03-29