99% Purity Factory Supply Rimonabant/Acomplia Powder for Weight-Loss CAS 168273-06-1

99% Purity Factory Supply  Rimonabant Powder For Weight-Loss CAS 168273-06-1


Rimonabant COA:







Company :




Brand Name Variations 

Other names for Rimonabant are Zimulti, Acomplia, Monaslim, Bethin, Riobant, Remonabent, Rimoslim and Riomont.

Quick Details:

Minimum Order Quantity:Negotiation

Price:Negotiation

Packaging Details:Discreet ways of packing for Customs pass guaranteed(1kg foil bag)

Leading time:Within 8hours after payment.(PS: USA based delievry could be available.)

Delivery time:Within 5working days after payment.

Payment method:Western Union,Money Gram,Bank Transfer,Bitcoin.

Supply Ability:100ton Per Month

Shipment Method: UPS DHL Fedex TNT EMS HKEMS HongKong post EUB ETK


Abstract

Rimonabant is a weight loss drug, can significantly reduce weight, reduce waist circumference and reduce risk factors for cardiovascular disease, but also can improve blood lipids and insulin resistance and metabolic syndrome, especially for the presence of clinical obesity or heart disease people at risk.

Rimonabant as a new weight loss drug, can also be used to quit smoking. Not only lose weight, but also lower blood pressure, cholesterol and blood sugar, clinical study found that subjects taking one to two months later, the weight can be reduced on average six to eight kilograms.

An experimental wonder drug, Rimonabant, helps you lose weight, quit smoking and it also helps protect your heart. Trials have shown that 33% of people on Rimonabant lost 10% of body weight and kept their weight down for two years - this is a record, no other diet drug has managed to keep a person's weight down for so long. The second 33% lost 5% of body weight and kept it down. As well as keeping you lean, the drug also helps you quit the smoking habit. This will be of great interest for many smokers who are afraid to give up because they say they will put on loads of weight if they do.


Ingredients 

The active ingredient in Rimonabant or Acomplia tablets is Rimonabant.


Rimonabant Application

Rimonabant is the new weight-loss drug, can be applied to smoking cessation. A new weight-loss drug rimonabant (Rimonabant), not only can lose weight, but also lower blood pressure, cholesterol and blood sugar, domestically year clinical study found that subjects taking one to two months later, weight average minus six to eight kilograms.

As well as keeping you lean, the drug also helps you quit the smoking habit. This will be of great interest for many smokers who are afraid to give up because they say they will put on loads of weight if they do (young female smokers worry about this the most).


Mechanism of Action 

Rimonabant selectively blocks the CB1 receptors that are present in the brain and other peripheral organs important in fat/lipid and glucose metabolism, including muscle, gastrointestinal tract, liver and adipose tissue. Basically, it switches off those brain circuits that are responsible for making people hungry while smoking cannabis. Acomplia, along with CB1 receptors, reduces the EC system's over-activity. The EC system includes many receptors like CB1 receptor and is responsible for regulating the weight of the body and controlling lipid, glucose metabolism, as well as energy balance.


Function 

Rimonabant / Acomplia is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. Rimonabant is approved in 38 countries including the E.U., Mexico, and Brazil.

Rimonabant / Acomplia,Developed by Sanofi-Aventis, Acomplia (Rimonabant) is a selective CB1 receptor antagonist. In other words, Rimonabant is intended to promote weight loss by reducing the total number of calories an individual consumes on a daily basis.

Rimonabant / Acomplia works by blocking endogenous from binding to neuronal CB1 receptors. The activation of these receptors by endogenous , such as anadamide, increases an individuals appetite. By blocking the activation of the receptors, appetite suppression may occur.


How does rimonabant work?

Acomplia acts by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism, including adipose tissue, the liver, gastrointestinal tract and muscle2.

Acomplia switches off the same brain circuits that make people hungry when they smoke cannabis.
CB1 receptor blockade with Acomplia acts to decrease the overactivity of the endocannabinoid system (EC system).3,4 The EC system is a recently characterised physiological system that includes receptors such as the CB1 receptor and it has been shown to play an important role in regulating body weight and in controlling energy balance, as well as glucose and lipid (or fat) metabolism.

What is Rimonabant used for?
 

1)  Rimonabant(Acomplia) was studied to be used complementary to diet and exercise to treat obese or overweight patients who suffer from type 2 diabetes and abnormal levels of fat in the blood.

2)  Sanofi argued that Acomplia could also prevent the risk of cardiovascular disease.

Patients with large waist circumference (102 cm in men and 88 cm in women) were said to most benefit from taking the drug.

3)  Smoking cessation

Rimonabant may also be found to be effective in assisting some smokers to quit smoking. first, to use rimonabant directly to aid in smoking cessation; second, to help prevent weight gain in former smokers.

Adverse Effects 
 

The side effects of Rimonabant are so many that they effectively counteract any positive effects that it may present. Even during the trials, it was reported that 1 patient out of every 8 dropped out of the said trials since the side effects became intolerable for them.

The biggest and the most adverse effects, however, were psychological. Depression has come to get associated as a severe side effect of Rimonabant. This depression was so serious that it required medical treatment to be managed. Because of Rimonabant's effectiveness against smoking, many people used it for smoking cessation and suffered from suicidal depression.

Many patients experienced and reported extreme anxiety levels after taking Rimonabant. Nausea is another side effect which was so severe that it started interfering with the patients' daily life.

To summarize, the adverse effects of Rimonabant are many -

• Gastrointestinal Problems - One of the noted side effects are diarrhea, dry mouth, loss of appetite, nausea, vomiting and other gastrointestinal disorders.
• Skin Problems - Excessive sweating and itching has been reported.
• Musculoskeletal Problems - Joint sprains, back pain, inflammation and pain in the tendons, and spasms and cramps in muscles are common side effects.
• Central Nervous System - Depression, memory loss, anxiety, mood changes, dizziness, diarrhea and sleep disorder.

Dosage:

It is expected that the usual dose of rimonabant will be 20 mg once daily before breakfast. No dosage adjustment is recommended for the elderly, but this agent should be used with caution in patients older than 75 years of age.

Although rimonabant can be used in patients with mild hepatic impairment, caution is advised in patients with moderate impairment. This medication is not recommended for those with severe hepatic impairment.

Rimonabant may be used cautiously in patients with mild-to-moderate renal impairment, but it is not recommended for patients who are severely renally impaired.

History 
 

It became available in UK in the beginning of July 2006 and by 2008, there were 56 countries where it was available. It was meant for people with a BMI greater than 30 or people whose BMI was greater than 27 but who had other risk factors like dyslipidemia and type 2-diabetes.

In June 2006, European Commission approved its sale and it was submitted to FDA for US approval. However, FDA's EMDAC voted against the drug, concluding that Sanofi-Aventis, the manufacturers of Rimonabant, had not demonstrated its safety effectively. In 2009, EMEA withdrew Acomplia, after suspending it in 2008, because of severe psychological side effects of the drug, such as suicidal tendencies. FDA never approved Rimonabant and therefore, it has never been marketed in the US.

Our main products includes:

Raw steroids Powder
Injection Anabolic Steroids(Finished Liquid,Send free filters)
Sarms
sex enhancement Drugs
Estrogen steroid hormones
Oral Steroid hormones
Anti Estrogen steroids
 
Local Anesthesia Drugs
Pharmaceutical raw materials
Weight Loss Powder
Nootropic  Chemicals
Anti-cancer/Anti-Aging Drugs
Hair Growth Whitening Series Drugs

 

How to Complete an Order?
 

Package&delivery







Our Service

1.Quality Product and Good Price
We offer absolute high quality product in customized or non-customized.If there are any problems in quality,please contact me as soon as possible.

2.Fast&Secure Shipping
Generally,for small quantity product,the product will be shipped by courier.
For bulk goods,usually you will receive the product within 15 working days.
The rate of passing customs is more than 90%.

3.Reshipping Policy
Even for the worst situation when the product is blocked by the customs,we can reship the product without any extra payment for the product.

4.Technical Supports
Our lab can customize the right product and support u with our top specialists.So if u have a recipe and need help just inform us.We can make experiments and get a good result.

99% Purity Factory Supply  Rimonabant Powder For Weight-Loss CAS 168273-06-1


Rimonabant COA:







Company :




Brand Name Variations 

Other names for Rimonabant are Zimulti, Acomplia, Monaslim, Bethin, Riobant, Remonabent, Rimoslim and Riomont.

Quick Details:

Minimum Order Quantity:Negotiation

Price:Negotiation

Packaging Details:Discreet ways of packing for Customs pass guaranteed(1kg foil bag)

Leading time:Within 8hours after payment.(PS: USA based delievry could be available.)

Delivery time:Within 5working days after payment.

Payment method:Western Union,Money Gram,Bank Transfer,Bitcoin.

Supply Ability:100ton Per Month

Shipment Method: UPS DHL Fedex TNT EMS HKEMS HongKong post EUB ETK


Abstract

Rimonabant is a weight loss drug, can significantly reduce weight, reduce waist circumference and reduce risk factors for cardiovascular disease, but also can improve blood lipids and insulin resistance and metabolic syndrome, especially for the presence of clinical obesity or heart disease people at risk.

Rimonabant as a new weight loss drug, can also be used to quit smoking. Not only lose weight, but also lower blood pressure, cholesterol and blood sugar, clinical study found that subjects taking one to two months later, the weight can be reduced on average six to eight kilograms.

An experimental wonder drug, Rimonabant, helps you lose weight, quit smoking and it also helps protect your heart. Trials have shown that 33% of people on Rimonabant lost 10% of body weight and kept their weight down for two years - this is a record, no other diet drug has managed to keep a person's weight down for so long. The second 33% lost 5% of body weight and kept it down. As well as keeping you lean, the drug also helps you quit the smoking habit. This will be of great interest for many smokers who are afraid to give up because they say they will put on loads of weight if they do.


Ingredients 

The active ingredient in Rimonabant or Acomplia tablets is Rimonabant.


Rimonabant Application

Rimonabant is the new weight-loss drug, can be applied to smoking cessation. A new weight-loss drug rimonabant (Rimonabant), not only can lose weight, but also lower blood pressure, cholesterol and blood sugar, domestically year clinical study found that subjects taking one to two months later, weight average minus six to eight kilograms.

As well as keeping you lean, the drug also helps you quit the smoking habit. This will be of great interest for many smokers who are afraid to give up because they say they will put on loads of weight if they do (young female smokers worry about this the most).


Mechanism of Action 

Rimonabant selectively blocks the CB1 receptors that are present in the brain and other peripheral organs important in fat/lipid and glucose metabolism, including muscle, gastrointestinal tract, liver and adipose tissue. Basically, it switches off those brain circuits that are responsible for making people hungry while smoking cannabis. Acomplia, along with CB1 receptors, reduces the EC system's over-activity. The EC system includes many receptors like CB1 receptor and is responsible for regulating the weight of the body and controlling lipid, glucose metabolism, as well as energy balance.


Function 

Rimonabant / Acomplia is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. Rimonabant is approved in 38 countries including the E.U., Mexico, and Brazil.

Rimonabant / Acomplia,Developed by Sanofi-Aventis, Acomplia (Rimonabant) is a selective CB1 receptor antagonist. In other words, Rimonabant is intended to promote weight loss by reducing the total number of calories an individual consumes on a daily basis.

Rimonabant / Acomplia works by blocking endogenous from binding to neuronal CB1 receptors. The activation of these receptors by endogenous , such as anadamide, increases an individuals appetite. By blocking the activation of the receptors, appetite suppression may occur.


How does rimonabant work?

Acomplia acts by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism, including adipose tissue, the liver, gastrointestinal tract and muscle2.

Acomplia switches off the same brain circuits that make people hungry when they smoke cannabis.
CB1 receptor blockade with Acomplia acts to decrease the overactivity of the endocannabinoid system (EC system).3,4 The EC system is a recently characterised physiological system that includes receptors such as the CB1 receptor and it has been shown to play an important role in regulating body weight and in controlling energy balance, as well as glucose and lipid (or fat) metabolism.

What is Rimonabant used for?
 

1)  Rimonabant(Acomplia) was studied to be used complementary to diet and exercise to treat obese or overweight patients who suffer from type 2 diabetes and abnormal levels of fat in the blood.

2)  Sanofi argued that Acomplia could also prevent the risk of cardiovascular disease.

Patients with large waist circumference (102 cm in men and 88 cm in women) were said to most benefit from taking the drug.

3)  Smoking cessation

Rimonabant may also be found to be effective in assisting some smokers to quit smoking. first, to use rimonabant directly to aid in smoking cessation; second, to help prevent weight gain in former smokers.

Adverse Effects 
 

The side effects of Rimonabant are so many that they effectively counteract any positive effects that it may present. Even during the trials, it was reported that 1 patient out of every 8 dropped out of the said trials since the side effects became intolerable for them.

The biggest and the most adverse effects, however, were psychological. Depression has come to get associated as a severe side effect of Rimonabant. This depression was so serious that it required medical treatment to be managed. Because of Rimonabant's effectiveness against smoking, many people used it for smoking cessation and suffered from suicidal depression.

Many patients experienced and reported extreme anxiety levels after taking Rimonabant. Nausea is another side effect which was so severe that it started interfering with the patients' daily life.

To summarize, the adverse effects of Rimonabant are many -

• Gastrointestinal Problems - One of the noted side effects are diarrhea, dry mouth, loss of appetite, nausea, vomiting and other gastrointestinal disorders.
• Skin Problems - Excessive sweating and itching has been reported.
• Musculoskeletal Problems - Joint sprains, back pain, inflammation and pain in the tendons, and spasms and cramps in muscles are common side effects.
• Central Nervous System - Depression, memory loss, anxiety, mood changes, dizziness, diarrhea and sleep disorder.

Dosage:

It is expected that the usual dose of rimonabant will be 20 mg once daily before breakfast. No dosage adjustment is recommended for the elderly, but this agent should be used with caution in patients older than 75 years of age.

Although rimonabant can be used in patients with mild hepatic impairment, caution is advised in patients with moderate impairment. This medication is not recommended for those with severe hepatic impairment.

Rimonabant may be used cautiously in patients with mild-to-moderate renal impairment, but it is not recommended for patients who are severely renally impaired.

History 
 

It became available in UK in the beginning of July 2006 and by 2008, there were 56 countries where it was available. It was meant for people with a BMI greater than 30 or people whose BMI was greater than 27 but who had other risk factors like dyslipidemia and type 2-diabetes.

In June 2006, European Commission approved its sale and it was submitted to FDA for US approval. However, FDA's EMDAC voted against the drug, concluding that Sanofi-Aventis, the manufacturers of Rimonabant, had not demonstrated its safety effectively. In 2009, EMEA withdrew Acomplia, after suspending it in 2008, because of severe psychological side effects of the drug, such as suicidal tendencies. FDA never approved Rimonabant and therefore, it has never been marketed in the US.

Our main products includes:

Raw steroids Powder
Injection Anabolic Steroids(Finished Liquid,Send free filters)
Sarms
sex enhancement Drugs
Estrogen steroid hormones
Oral Steroid hormones
Anti Estrogen steroids
 
Local Anesthesia Drugs
Pharmaceutical raw materials
Weight Loss Powder
Nootropic  Chemicals
Anti-cancer/Anti-Aging Drugs
Hair Growth Whitening Series Drugs

 

How to Complete an Order?
 

Package&delivery







Our Service

1.Quality Product and Good Price
We offer absolute high quality product in customized or non-customized.If there are any problems in quality,please contact me as soon as possible.

2.Fast&Secure Shipping
Generally,for small quantity product,the product will be shipped by courier.
For bulk goods,usually you will receive the product within 15 working days.
The rate of passing customs is more than 90%.

3.Reshipping Policy
Even for the worst situation when the product is blocked by the customs,we can reship the product without any extra payment for the product.

4.Technical Supports
Our lab can customize the right product and support u with our top specialists.So if u have a recipe and need help just inform us.We can make experiments and get a good result.